[step:Exhibit a positively-oriented diffeomorphism onto $-U$ via reflection of the first coordinate]The opposite orientation on $-U$ is, by definition, the orientation for which a diffeomorphism $\psi: V \to U$ (with $V \subseteq \mathbb{R}^n$ open) is positively oriented iff its Jacobian determinant is strictly negative everywhere. We construct such a $\psi$ explicitly. Let
\begin{align*}
V := \{(y_1, y_2, \ldots, y_n) \in \mathbb{R}^n : (-y_1, y_2, \ldots, y_n) \in U\},
\end{align*}
which is open in $\mathbb{R}^n$ because it is the preimage of $U$ under the continuous map $y \mapsto (-y_1, y_2, \ldots, y_n)$. Define
\begin{align*}
\psi: V &\to U \\
(y_1, y_2, \ldots, y_n) &\mapsto (-y_1, y_2, \ldots, y_n).
\end{align*}
Then $\psi$ is a smooth bijection with smooth inverse $y \mapsto (-y_1, y_2, \ldots, y_n)$ (the same formula), so $\psi$ is a diffeomorphism. Its Jacobian matrix is $\operatorname{diag}(-1, 1, \ldots, 1)$, hence $\det J\psi_y = -1 < 0$ for every $y \in V$. Therefore $\psi$ is a positively-oriented chart for $-U$.[/step]