[step:Identify sheaf cohomology with Dolbeault cohomology]
Let $\mathcal{O}(E)$ denote the sheaf of holomorphic sections of the holomorphic vector bundle $E \to X$, and let $\mathcal{O}(K_X \otimes E^*)$ denote the sheaf of holomorphic sections of $K_X \otimes E^* \to X$. For each integer $r$, let $A^{0,r}(X,E)$ denote the complex [vector space](/page/Vector%20Space) of smooth $E$-valued $(0,r)$-forms on $X$, with the convention that $A^{0,r}(X,E)=0$ if $r<0$ or $r>n$. Let
\begin{align*}
\bar{\partial}_E: A^{0,r}(X,E) \to A^{0,r+1}(X,E)
\end{align*}
denote the Dolbeault operator induced by the holomorphic structure on $E$. Similarly, let
\begin{align*}
\bar{\partial}_{K_X \otimes E^*}: A^{0,r}(X,K_X \otimes E^*) \to A^{0,r+1}(X,K_X \otimes E^*)
\end{align*}
denote the Dolbeault operator on $K_X \otimes E^*$, where $A^{0,r}(X,K_X \otimes E^*)$ has the same zero convention outside $0 \leq r \leq n$. Define the Dolbeault cohomology groups by
\begin{align*}
H^r_{\bar{\partial}}(X,E)
&:=
\frac{\ker(\bar{\partial}_E: A^{0,r}(X,E) \to A^{0,r+1}(X,E))}
{\operatorname{im}(\bar{\partial}_E: A^{0,r-1}(X,E) \to A^{0,r}(X,E))}, \\
H^r_{\bar{\partial}}(X,K_X \otimes E^*)
&:=
\frac{\ker(\bar{\partial}_{K_X \otimes E^*}: A^{0,r}(X,K_X \otimes E^*) \to A^{0,r+1}(X,K_X \otimes E^*))}
{\operatorname{im}(\bar{\partial}_{K_X \otimes E^*}: A^{0,r-1}(X,K_X \otimes E^*) \to A^{0,r}(X,K_X \otimes E^*))}.
\end{align*}
By the Dolbeault theorem for holomorphic vector bundles (citing a result not yet in the wiki: Dolbeault theorem for holomorphic vector bundles), there are natural isomorphisms
\begin{align*}
H^q(X,\mathcal{O}(E))
&\cong
\frac{\ker(\bar{\partial}_E: A^{0,q}(X,E) \to A^{0,q+1}(X,E))}
{\operatorname{im}(\bar{\partial}_E: A^{0,q-1}(X,E) \to A^{0,q}(X,E))}, \\
H^{n-q}(X,\mathcal{O}(K_X \otimes E^*))
&\cong
\frac{\ker(\bar{\partial}_{K_X \otimes E^*}: A^{0,n-q}(X,K_X \otimes E^*) \to A^{0,n-q+1}(X,K_X \otimes E^*))}
{\operatorname{im}(\bar{\partial}_{K_X \otimes E^*}: A^{0,n-q-1}(X,K_X \otimes E^*) \to A^{0,n-q}(X,K_X \otimes E^*))}.
\end{align*}
Thus it is enough to construct and prove nondegeneracy of the pairing on Dolbeault cohomology.
[/step]