[guided]The estimator is unbiased because the likelihood ratio $L$ changes the sampling measure $\mathbb Q$ back into the target measure $\mathbb P$. We must first check that the target integral is a genuine finite number. Since $L=d\mathbb P/d\mathbb Q$, the Radon--Nikodym integration identity says that for every non-negative measurable function $g:S\to[0,\infty]$,
\begin{align*}
\int_S g(s)\,d\mathbb P(s)=\int_S g(s)L(s)\,d\mathbb Q(s).
\end{align*}
Apply this with $g=|h|$. We obtain
\begin{align*}
\int_S |h(s)|\,d\mathbb P(s)=\int_S |h(s)|L(s)\,d\mathbb Q(s).
\end{align*}
The assumption $hL\in L^2(S,\mathcal S,\mathbb Q)$ implies $hL\in L^1(S,\mathcal S,\mathbb Q)$ because $\mathbb Q(S)=1$. More explicitly, Cauchy--Schwarz applied to the functions $|h|L$ and $1$ on the probability space $(S,\mathcal S,\mathbb Q)$ gives
\begin{align*}
\int_S |h(s)|L(s)\,d\mathbb Q(s)\le \left(\int_S h(s)^2L(s)^2\,d\mathbb Q(s)\right)^{1/2}\left(\int_S 1\,d\mathbb Q(s)\right)^{1/2}<\infty.
\end{align*}
Thus $h$ is $\mathbb P$-integrable, and the number
\begin{align*}
I=\int_S h(s)\,d\mathbb P(s)
\end{align*}
is well-defined.
Now fix $i\in\{1,\dots,N\}$. Since $Y_i$ has law $\mathbb Q$, the expectation of the composition $g\circ Y_i$ is the integral of $g$ against $\mathbb Q$:
\begin{align*}
\mathbb E_{\mathbb P_0}[X_i]=\int_S g(s)\,d\mathbb Q(s)=\int_S h(s)L(s)\,d\mathbb Q(s),
\end{align*}
where the second equality uses $g=hL$ $\mathbb Q$-a.e. Applying the Radon--Nikodym identity to the integrable function $h$ gives
\begin{align*}
\int_S h(s)L(s)\,d\mathbb Q(s)=\int_S h(s)\,d\mathbb P(s)=I.
\end{align*}
Therefore every summand has mean $I$. Since the estimator is the arithmetic average of these summands,
\begin{align*}
\mathbb E_{\mathbb P_0}[\widehat I_{N,\mathrm{IS}}]=\mathbb E_{\mathbb P_0}\left[\frac{1}{N}\sum_{i=1}^N X_i\right]=\frac{1}{N}\sum_{i=1}^N \mathbb E_{\mathbb P_0}[X_i]=I.
\end{align*}[/guided]