[guided]First we check that the energies are well-defined finite numbers. Let $v\in W^{1,p}(U)$. The [Measurability of Caratheodory Compositions][citetheorem:8735] gives that $x\mapsto f(x,v(x),\nabla v(x))$ is Lebesgue measurable on $U$. The upper growth hypothesis gives
\begin{align*}
0\le f(x,v(x),\nabla v(x))\le C(1+|v(x)|^p+|\nabla v(x)|^p)
\end{align*}
for $\mathcal L^n$-a.e. $x\in U$. Since $U$ is bounded, $\mathcal L^n(U)<\infty$; since $v\in W^{1,p}(U)$, both $v$ and $\nabla v$ belong to the corresponding $L^p$ spaces. Therefore the right-hand side is integrable over $U$, and $I[v]\in[0,\infty)$.
The quantity we must compare with $I[u]$ is the limit inferior of the sequence of energies. Since every energy is nonnegative, the limit inferior belongs to $[0,\infty]$. Define
\begin{align*}
\alpha:=\liminf_{k\to\infty} I[u_k].
\end{align*}
If $\alpha=+\infty$, then there is no estimate to prove beyond nonnegativity: the integrand $f$ takes values in $[0,\infty)$, so
\begin{align*}
I[u]=\int_U f(x,u(x),\nabla u(x))\,d\mathcal L^n(x)\ge 0,
\end{align*}
and hence $I[u]\le+\infty$.
We may therefore assume $\alpha<+\infty$. The definition of $\liminf$ gives a subsequence whose energy converges to $\alpha$. More explicitly, there exists a strictly increasing sequence $(k_j)_{j=1}^{\infty}$ of natural numbers such that
\begin{align*}
\lim_{j\to\infty} I[u_{k_j}]=\alpha.
\end{align*}
Thus, if we prove the lower semicontinuity inequality along this subsequence,
\begin{align*}
I[u]\le \liminf_{j\to\infty} I[u_{k_j}],
\end{align*}
then the right-hand side equals $\alpha$, and we obtain exactly
\begin{align*}
I[u]\le \liminf_{k\to\infty} I[u_k].
\end{align*}[/guided]